SNIPER

Blood Cancer
Ultra-sensitive detection of minimal residual disease and gene mutations in hematologic malignancies using digital PCR.

Explore Our Diagnostic Portfolio

Available Tests: 38

Fusion Gene MRD Detection

BCR::ABL1 p210

Quantitative detection of BCR-ABL1 mRNA copy number is performed using digital PCR, applicable to 97% of CML cases. It can be used for CML diagnosis and classification, treatment response evaluation, prognosis assessment, and minimal residual disease (MRD) monitoring.

Sample

Peripheral blood, Bone marrow

BCR::ABL1 p190

Quantitative detection of BCR-ABL1 mRNA copy number is performed using digital PCR. This assay supports studies on disease classification, treatment response, prognosis, and MRD monitoring in CML and ALL.

Sample

Peripheral blood, Bone marrow

BCR::ABL1 p230

Quantitative detection of BCR-ABL1 mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in CML.

Sample

Peripheral blood, Bone marrow

AML::ETO

Quantitative detection of AML1-ETO (RUNX1-RUNX1T1) mRNA is performed using digital PCR. Supports research on classification, treatment response, prognosis, and MRD monitoring in AML, especially AML-M2b.

Sample

Peripheral blood, Bone marrow

PML::RARα (L-Type)

Quantitative detection of PML-RARα mRNA is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in APL.

Sample

Peripheral blood, Bone marrow

PML::RARα (S-Type)

Quantitative detection of PML-RARα mRNA is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in APL.

Sample

Peripheral blood, Bone marrow

PML::RARα (V-Type)

Quantitative detection of PML-RARα mRNA is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in APL.

Sample

Peripheral blood, Bone marrow

MLL::AF9

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

MLL::AF6

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

MLL::AF4

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

MLL::AF10

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

MLL::ELL

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

MLL::ENL

Quantitative detection of MLL fusion transcripts (AF9, AF6, AF4, AF10, ELL, ENL) is performed using digital PCR. This assay supports AML and T-ALL studies involving subtype classification, prognosis, and MRD tracking.

Sample

Peripheral blood, Bone marrow

CBFβ::MYH11

Quantitative detection of CBFβ-MYH11 mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in AML.

Sample

Peripheral blood, Bone marrow

E2A::PBX1

Quantitative detection of E2A-HLF mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in ALL, especially precursor B-ALL.

Sample

Peripheral blood, Bone marrow

E2A::HLF

Quantitative detection of E2A-HLF mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in ALL, especially precursor B-ALL.

Sample

Peripheral blood, Bone marrow

SIL::TAL1

Quantitative detection of SIL-TAL1 mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in T-ALL.

Sample

Peripheral blood, Bone marrow

TEL::AML1

Quantitative detection of TEL-AML1 mRNA expression level, which can be used for ALL especially B-ALL diagnosis and classification, efficacy assessment, prognosis assessment and MRD monitoring.

Sample

Peripheral blood, Bone marrow

DEK::CAN

Quantitative detection of DEK-CAN mRNA copy number is performed using digital PCR. This assay supports studies on classification, treatment response, prognosis, and MRD monitoring in AML. It is also observed in MDS and CML.

Sample

Peripheral blood, Bone marrow

Mutation Detection

WT1 mRNA

Quantitative detection of WT1 mRNA copy number and its expression relative to ABL1 is performed using digital PCR. This assay supports studies on treatment response, prognosis, and MRD monitoring in AL and CML.

Sample

Peripheral blood, Bone marrow

MYD88 L265P

Detection of the MYD88 L265P mutation is performed using digital PCR. This assay supports studies on classification, drug guidance, and prognosis in lymphoplasmacytic lymphoma/Waldenström’s macroglobulinemia (LPL/WM).

Sample

Peripheral blood

KIT D816V

Detection of C-KIT gene mutations D816V, D816Y, and D816H is performed using digital PCR. This assay supports studies on treatment response and prognosis in AML.

Sample

Peripheral blood

KIT D816Y

Detection of C-KIT gene mutations D816V, D816Y, and D816H is performed using digital PCR. This assay supports studies on treatment response and prognosis in AML.

Sample

Peripheral blood

KIT D816H

Detection of C-KIT gene mutations D816V, D816Y, and D816H is performed using digital PCR. This assay supports studies on treatment response and prognosis in AML.

Sample

Peripheral blood

N822K (A-Type/G-Type)

Detection of the C-KIT N822K mutation is performed using digital PCR. This assay supports studies on treatment response and prognosis in CBF-AML.

Sample

Peripheral blood

JAK2 V617F

Detection of the JAK2 V617F mutation is performed using digital PCR. This assay supports studies on auxiliary diagnosis, therapeutic monitoring, and prognosis in myeloproliferative disorders (MPD), including PV, ET, and IMF.

Sample

Peripheral blood

JAK2/MPL/CALR

Detection of the JAK2/MPL/CALR mutation is performed using digital PCR. This assay supports studies on auxiliary diagnosis, therapeutic monitoring, and prognosis in myeloproliferative disorders (MPD), including PV, ET, and IMF.

Sample

Peripheral blood

DNMT3A R882

Detection of the DNMT3A R882 mutation is performed using digital PCR. This assay supports studies on prognosis in AML.

Sample

Peripheral blood

FLT3 D835, I836

Detection of FLT3 gene mutations D835 and D836 is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

NPM1 (A-Type/B-Type/D-Type)

Detection of NPM1 gene mutation is performed using digital PCR. This assay supports studies on prognosis and MRD monitoring in AML.

Sample

Peripheral blood

IDH1 R132L

Detection of the IDH1 R132L mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH1 R132V

Detection of the IDH1 R132V mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH1 R132C

Detection of the IDH1 R132C mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH1 R132G

Detection of the IDH1 R132G mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH1 R132H

Detection of the IDH1 R132H mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH1 R132S

Detection of the IDH1 R132S mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH2 R140Q

Detection of the IDH2 R140 mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood

IDH2 R172K

Detection of the IDH1 R172 mutation is performed using digital PCR. This assay supports studies on drug guidance and prognosis in AML.

Sample

Peripheral blood